Top Guidelines Of phenobarbital sodium tablets
Top Guidelines Of phenobarbital sodium tablets
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benzhydrocodone/acetaminophen and pentobarbital both of those enhance sedation. Avoid or Use Alternate Drug. Restrict use to patients for whom alternative remedy alternatives are insufficient
pentobarbital will decrease the extent or effect of mavacamten by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
Contraindicated (one)pentobarbital will decrease the level or effect of lumacaftor/ivacaftor by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will minimize the level or effect of linagliptin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. Use of alternative therapies is strongly suggested when linagliptin will be to be administered with a CYP3A4 inducer
Contraindicated (1)pentobarbital decreases levels of panobinostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Solid CYP3A4 inducers can minimize panobinostat concentrations by ~70% and bring about procedure failure.
pentobarbital will decrease the level or effect of maraviroc by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
Monoamine oxidase inhibitors (MAOI): MAOI prolong the effects of barbiturates likely since metabolism on the barbiturate is inhibited.
pentobarbital will lower the extent or effect of more info estropipate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
Fetal blood degrees technique maternal blood amounts following parenteral administration. Withdrawal symptoms occur in infants born to mothers who get barbiturates all through the final trimester of pregnancy. (See “Drug Abuse and Dependence” section.) If this drug is used throughout pregnancy, or When the affected individual will become Expecting even though having this drug, the affected person should be apprised with the possible hazard into the fetus.
pentobarbital will minimize the level or effect of trazodone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will lower the extent or effect of eltrombopag by influencing hepatic enzyme CYP2C9/10 metabolism. Use Caution/Watch.
pentobarbital will decrease the level or effect of mifepristone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. CYP3A4 inducers haven't been examined, coadministration not suggested by producer
pentobarbital will lessen the extent or effect of cobimetinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Stay clear of coadministration. Robust or moderate CYP3A inducers may well reduce cobimetinib systemic publicity by >80% and lessen its efficacy.
pentobarbital will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.